YAP Antibody (H-9): sc-271134
- YAP Antibody (H-9) is a mouse monoclonal IgG1 κ, cited in 70 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 379-407 near the C-terminus of YAP of human origin
- Anti-YAP Antibody (H-9) is recommended for detection of YAP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- YAP Antibody (H-9) is available conjugated to Alexa Fluor® 546 or Alexa Fluor® 594 for WB (RGB), IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-271134 X, 200 µg/0.1 ml)
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of YAP (H-9): sc-271134.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for YAP Antibody (H-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with YAP Antibody (H-9) (see ordering information below).
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SEE ALSO...
YAP Antibody (H-9) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect Yes-associated protein (YAP), also known as YAP1, across multiple species including mouse, rat, and human. YAP monoclonal antibody (H-9) targets a precise epitope located between amino acids 379-407 near the C-terminus of human YAP, ensuring robust and accurate binding in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). YAP is a pivotal component of the Hippo signaling pathway, functioning as a transcriptional co-activator that regulates essential cellular processes including cell proliferation, apoptosis, and organ size. The localization of YAP within the cell, whether in the nucleus or cytoplasm, is crucial for controlling gene expression and maintaining cellular homeostasis. By interacting with 14-3-3 proteins, YAP′s activity and subcellular distribution are tightly regulated, linking extracellular signals to nuclear responses that influence cell differentiation, cell cycle progression, and programmed cell death. This regulation is vital for normal physiological functions and is implicated in the development of various cancers when dysregulated. Additionally, YAP shares structural homology with TAZ (transcriptional co-activator with PDZ-binding motif), highlighting its significance in complex cellular signaling networks. Expressed abundantly in tissues such as the lung, placenta, prostate, ovary, and testis, anti-YAP antibody (H-9) serves as an indispensable tool for researchers aiming to elucidate the intricate mechanisms of YAP′s function and its role in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
YAP Antibody (H-9) | sc-271134 | 200 µg/ml | $316.00 | |||
YAP Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-525787 | 200 µg Ab; 10 µg BP | $354.00 | |||
YAP Antibody (H-9) X | sc-271134 X | 200 µg/0.1 ml | $316.00 | |||
YAP Antibody (H-9) Alexa Fluor® 546 | sc-271134 AF546 | 200 µg/ml | $357.00 | |||
YAP Antibody (H-9) Alexa Fluor® 594 | sc-271134 AF594 | 200 µg/ml | $357.00 | |||
YAP Antibody (H-9) Alexa Fluor® 680 | sc-271134 AF680 | 200 µg/ml | $357.00 | |||
YAP Antibody (H-9) Alexa Fluor® 790 | sc-271134 AF790 | 200 µg/ml | $357.00 | |||
YAP (H-9) Neutralizing Peptide | sc-271134 P | 100 µg/0.5 ml | $68.00 |